Selected Publications
* Authors contributed equally to this work
# Corresponding author
# Corresponding author
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Lama-Diaz T., Blanco M.G. Alternative translation initiation by ribosomal leaky scanning produces multiple isoforms of the Pif1 helicase. Nucleic Acids Res. 2024; 52 (12): 6928-6944. DOI: 10.1093/nar/gkae400. |
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Carreira R., Lama-Diaz T.*, Crugeiras M.*, Aguado F.J., Sebesta M., Krejci L., Blanco M.G. Concurrent D-loop cleavage by Mus81 and Yen1 yields half-crossover precursors. Nucleic Acids Res. 2024; 52 (12): 7012-7030. DOI: 10.1093/nar/gkae453. |
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Carreira R.*, Aguado F.J.*, Hurtado-Nieves V., Blanco M.G. Canonical and novel non-canonical activities of the Holliday junction resolvase Yen1. Nucleic Acids Res. 2022; 50 (1): 259-280.
DOI: 10.1093/nar/gkab1225. |
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Morafraile E.C., Bugallo A., Carreira R., Fernández M., Martín-Castellanos C., Blanco M.G., Segurado M. Exo1 phosphorylation inhibits exonuclease activity and prevents fork collapse in rad53 mutants independently of the 14-3-3 proteins. Nucleic Acids Res. 2020; 48 (6): 3053-3070.
DOI: 10.1093/nar/gkaa054. |
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Arter M., Hurtado-Nieves V.*, Oke A.*, Zhuge T., Wettstein R., Fung J.C., Blanco M.G.#, Matos J.# Regulated crossing-over requires inactivation of Yen1/GEN1 resolvase during meiotic prophase I. Dev. Cell 2018; 45 (6): 785-800.
DOI: 10.1016/j.devcel.2018.05.020. |
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Guallar D., Bi X., Pardavila J.A., Huang X., Saenz C., Shi X., Zhou H., Faiola F., Ding J., Haruehanroengra P., Yang F., Li D., Sanchez-Priego C., Saunders A., Pan F., Valdes V.J., Kelley K., Blanco M.G., Chen L., Wang H., Sheng J., Xu M., Fidalgo M., Shen X., Wang J. RNA-dependent chromatin targeting of TET2 for endogenous retrovirus control in pluripotent stem cells. Nat. Genet. 2018; 50: 443–451. DOI: 10.1038/s41588-018-0060-9. |
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Princz L.N., Wild P., Bittmann J., Aguado F.J., Blanco M.G., Matos J., Pfander B. D. Dbf4-dependent kinase and the Rtt107 scaffold promote Mus81-Mms4 resolvase activation during mitosis. EMBO J. 2017; 36: 664-678.
DOI: 10.15252/embj.201694831. |
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Duda H., Arter M., Gloggnitzer J., Teloni F., Wild P., Blanco, M.G., Altmeyer M., Matos, J. A Mechanism for Controlled Breakage of Under-replicated Chromosomes during Mitosis. Dev. Cell 2016; 39: 740-755.
DOI: 10.1016/j.devcel.2016.11.017. |
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Blanco M.G.#, Matos J.# Hold your horSSEs: controlling structure-selective endonucleases MUS81 and Yen1/GEN1. Front. Genet. 2015; 6: 253.
DOI: 10.3389/fgene.2015.00253 |
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Blanco M.G.*, Matos J.*, West S.C. Dual Control of Yen1 Nuclease Activity and Cellular Localization by Cdk and Cdc14 Prevents Genome Instability. Mol. Cell. 2014; 54: 94-106.
DOI: 10.1016/j.molcel.2014.02.011. |
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Matos J.*, Blanco M.G.*, Maslen S., Skehel J.M. & West S.C. Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis. Cell 2011; 147: 158-72.
DOI: 10.1016/j.cell.2011.08.032. |
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Blanco M.G., Matos J., Rass U., Ip S.C.Y. & West S.C. Functional overlap between the structure-specific nucleases Yen1 and Mus81-Mms4 for DNA-damage repair in S. cerevisiae. DNA Repair 2010; 9: 394-402.
DOI: 10.1016/j.dnarep.2009.12.017. |
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Ip S.C.*, Rass U.*, Blanco M.G.*, Flynn H.R., Skehel J.M., West S.C. Identification of Holliday junction resolvases from humans and yeast. Nature 2008; 456: 357-61.
DOI: 10.1038/nature07470. |
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Boán F.* Blanco M.G*., González A., Barros P. and Gómez-Márquez J. Inhibition of DNA synthesis by K+-stabilised G-quadruplex promotes allelic preferential amplification. FEBS Lett. 2004; 571: 112-118.
DOI: 10.1016/j.febslet.2004.06.062. |
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Blanco M.G.*, Boán F.* and Gómez-Márquez J. A paradox in the in vitro end-joining assays. J. Biol. Chem. 2004; 279: 26797-26801.
DOI: 10.1074/jbc.M402832200. |
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